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Chapter 5 · Evidences that DNA is the Genetic Material: practice questions

Chapter 5 — DNA and Genetic Information · Biology. These are 10 questions from the Magmo3 bank on this lesson, from easy to hard. Solve each one, then open "Show answer and explanation". Magmo3 has 33 questions on this lesson, each with an explanation.

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Question 1Easy

Which scientist carried out the transformation experiment on pneumonia bacteria?

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Correct answer: (C) Griffith

Explanation: In 1928, Griffith found that some factor from heat-killed virulent (S) bacteria converts non-virulent (R) bacteria into virulent ones. He called this bacterial transformation.

Question 2Easy

In Griffith's experiment, the strain that causes the mouse to die when injected while alive is:

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Correct answer: (B) the virulent S strain

Explanation: Live virulent S kills the mouse. Live R alone is non-virulent (it causes pneumonia but not death), and heat-killed S alone does not kill it either.

Question 3Easy

A bacteriophage is composed mainly of:

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Correct answer: (A) DNA and a protein coat

Explanation: The phage is simple: an outer protein coat and DNA inside.

Question 4Medium

When Griffith injected the mouse with heat-killed S bacteria together with live R bacteria, the result was:

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Correct answer: (D) the mouse died and live S bacteria were found in it

Explanation: The R was transformed into virulent S by a substance from the dead S, so the mouse died and live S was found in it.

Question 5Medium

The shared conclusion from the experiments of Avery and of Hershey and Chase is that:

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Correct answer: (A) DNA is the genetic material

Explanation: Both experiments confirmed that DNA, not protein, is the genetic material.

Question 6Medium

When Avery and his colleagues broke down the protein and RNA in the extract, transformation:

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Correct answer: (C) continued normally

Explanation: Breaking down the protein and RNA did not affect transformation, meaning they are not the genetic material.

Question 7Medium

The conclusion Hershey and Chase reached was that what entered the bacteria and formed new phages was the:

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Correct answer: (D) DNA

Explanation: The phosphorus-labeled DNA entered the bacteria, while the sulfur-labeled protein remained outside.

Question 8Hard

If the radioactivity of sulfur had appeared inside the bacteria in the Hershey-Chase experiment, this would have indicated that:

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Correct answer: (A) the protein entered and could be the genetic material

Explanation: Sulfur labels the protein, so if it had entered, that would mean the protein entered; but this did not happen, and what entered was the DNA.

Question 9Hard

Suppose the blender step were left out of the Hershey–Chase experiment with sulfur-labelled phages. Where would most of the radioactivity end up after centrifuging?

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Correct answer: (C) In the pellet, because the empty coats stay attached to the bacteria

Explanation: The blender's job is to shake the empty protein coats off the bacterial surface. Without it, the coats stay stuck to the bacteria and settle with them in the pellet. The result would wrongly suggest that protein entered.

Question 10Hard

Measurements in one animal species gave the DNA per nucleus as: liver cell 6.6 units, kidney cell 6.6 units, sperm 3.3 units. Protein per nucleus differed from tissue to tissue. Which conclusion do these data support?

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Correct answer: (C) DNA is constant in body cells and halved in gametes, as genes should be

Explanation: The genetic material should be equal in all body cells of a species and half as much in gametes, which carry one set of chromosomes. DNA fits this pattern; protein, which varies between tissues, does not.

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