Chapter 5 · Evidences that DNA is the Genetic Material: practice questions
Chapter 5 — DNA and Genetic Information · Biology. These are 10 questions from the Magmo3 bank on this lesson, from easy to hard. Solve each one, then open "Show answer and explanation". Magmo3 has 33 questions on this lesson, each with an explanation.
Which scientist carried out the transformation experiment on pneumonia bacteria?
AWatson
BAvery
CGriffith
DMendel
Show answer and explanation
Correct answer: (C) Griffith
Explanation: In 1928, Griffith found that some factor from heat-killed virulent (S) bacteria converts non-virulent (R) bacteria into virulent ones. He called this bacterial transformation.
Question 2Easy
In Griffith's experiment, the strain that causes the mouse to die when injected while alive is:
Athe heat-killed S strain
Bthe virulent S strain
Cthe non-virulent R strain
Dthe heat-killed R strain
Show answer and explanation
Correct answer: (B) the virulent S strain
Explanation: Live virulent S kills the mouse. Live R alone is non-virulent (it causes pneumonia but not death), and heat-killed S alone does not kill it either.
Question 3Easy
A bacteriophage is composed mainly of:
ADNA and a protein coat
Blipids and sugars
Csugar and phosphate only
Dprotein only
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Correct answer: (A) DNA and a protein coat
Explanation: The phage is simple: an outer protein coat and DNA inside.
Question 4Medium
When Griffith injected the mouse with heat-killed S bacteria together with live R bacteria, the result was:
Athe mouse lived and the live R bacteria were killed in it
Bno change occurred in the mouse or in the bacteria
Cthe mouse lived normally with no S bacteria found in it
Dthe mouse died and live S bacteria were found in it
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Correct answer: (D) the mouse died and live S bacteria were found in it
Explanation: The R was transformed into virulent S by a substance from the dead S, so the mouse died and live S was found in it.
Question 5Medium
The shared conclusion from the experiments of Avery and of Hershey and Chase is that:
ADNA is the genetic material
BRNA is the genetic material
Csugar is the genetic material
Dprotein is the genetic material
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Correct answer: (A) DNA is the genetic material
Explanation: Both experiments confirmed that DNA, not protein, is the genetic material.
Question 6Medium
When Avery and his colleagues broke down the protein and RNA in the extract, transformation:
Astopped completely
Bmade all the bacteria disappear
Ccontinued normally
Ddoubled
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Correct answer: (C) continued normally
Explanation: Breaking down the protein and RNA did not affect transformation, meaning they are not the genetic material.
Question 7Medium
The conclusion Hershey and Chase reached was that what entered the bacteria and formed new phages was the:
Aouter coat
Bprotein
Cfree phosphate
DDNA
Show answer and explanation
Correct answer: (D) DNA
Explanation: The phosphorus-labeled DNA entered the bacteria, while the sulfur-labeled protein remained outside.
Question 8Hard
If the radioactivity of sulfur had appeared inside the bacteria in the Hershey-Chase experiment, this would have indicated that:
Athe protein entered and could be the genetic material
Bthe phosphorus disappeared from the DNA of the phage
CDNA is the genetic material, since sulfur labels the DNA
Dthe phage died before it could infect the bacteria
Show answer and explanation
Correct answer: (A) the protein entered and could be the genetic material
Explanation: Sulfur labels the protein, so if it had entered, that would mean the protein entered; but this did not happen, and what entered was the DNA.
Question 9Hard
Suppose the blender step were left out of the Hershey–Chase experiment with sulfur-labelled phages. Where would most of the radioactivity end up after centrifuging?
AIn the liquid, because protein coats are always lighter than bacteria
BSpread evenly, because sulfur does not stay in protein without blending
CIn the pellet, because the empty coats stay attached to the bacteria
DInside the new phages, because the labelled coats are reused
Show answer and explanation
Correct answer: (C) In the pellet, because the empty coats stay attached to the bacteria
Explanation: The blender's job is to shake the empty protein coats off the bacterial surface. Without it, the coats stay stuck to the bacteria and settle with them in the pellet. The result would wrongly suggest that protein entered.
Question 10Hard
Measurements in one animal species gave the DNA per nucleus as: liver cell 6.6 units, kidney cell 6.6 units, sperm 3.3 units. Protein per nucleus differed from tissue to tissue. Which conclusion do these data support?
ASperm carry half the genes of the species, so they are genetically defective
BProtein is the genetic material because it changes with the cell's function
CDNA is constant in body cells and halved in gametes, as genes should be
DDNA cannot be the genetic material because sperm contain less of it
Show answer and explanation
Correct answer: (C) DNA is constant in body cells and halved in gametes, as genes should be
Explanation: The genetic material should be equal in all body cells of a species and half as much in gametes, which carry one set of chromosomes. DNA fits this pattern; protein, which varies between tissues, does not.