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Chapter 5 · Mutations: practice questions

Chapter 5 — DNA and Genetic Information · Biology. These are 10 questions from the Magmo3 bank on this lesson, from easy to hard. Solve each one, then open "Show answer and explanation". Magmo3 has 36 questions on this lesson, each with an explanation.

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Question 1Easy

A gene mutation occurs at the level of?

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Correct answer: (B) The sequence of nitrogenous bases within the gene

Explanation: A gene mutation is a change in the sequence of nitrogenous bases within the gene itself.

Question 2Easy

The agents that cause mutations are called?

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Correct answer: (B) Mutagens

Explanation: Mutagens are the agents that increase the rate at which mutations occur.

Question 3Easy

Are all mutations harmful?

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Correct answer: (B) No, there are also beneficial or neutral mutations

Explanation: Mutations may be harmful, neutral (having no effect), or beneficial, and beneficial mutations are the basis of variation and evolution.

Question 4Medium

A substitution mutation means?

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Correct answer: (A) Replacing one nitrogenous base with another in the DNA

Explanation: In substitution, one nitrogenous base is replaced by another, and this is a type of point mutation.

Question 5Medium

A missense mutation, in its effect?

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Correct answer: (C) Changes a single amino acid in the protein

Explanation: In a missense mutation the codon changes into one coding for a different amino acid, so a single amino acid in the protein changes.

Question 6Medium

A mutation that occurs in the sex cells (gametes)?

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Correct answer: (B) Is passed on to the following generations

Explanation: A mutation in the sex cells is inherited by the offspring, unlike a somatic mutation, which affects only the individual itself.

Question 7Medium

Inversion of a segment of a chromosome means?

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Correct answer: (C) A segment detaches and returns to the same place in reversed order

Explanation: In inversion, a segment of the chromosome detaches and returns to its place but with a reversed gene order.

Question 8Hard

Down syndrome results from?

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Correct answer: (D) An extra copy of chromosome 21 (trisomy)

Explanation: Down syndrome is a numerical chromosomal mutation: 3 copies of chromosome 21 instead of 2, making the total 47 chromosomes.

Question 9Hard

A point mutation changed a codon for an amino acid into a stop codon. The most likely result?

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Correct answer: (D) Protein synthesis stops early, producing a short non-functional protein

Explanation: This is a nonsense mutation: an early stop codon halts translation, producing an incomplete, usually non-functional protein.

Question 10Hard

An insertion of 3 consecutive bases within a gene is most likely to?

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Correct answer: (A) Add a single amino acid without shifting the reading frame

Explanation: Adding a number of bases that is a multiple of 3 adds or removes amino acids without shifting the reading frame, so the effect is less than a frameshift.

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The first 10 questions in every subject are free, each with an explanation.

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