Chapter 6 · RNAs, the Genetic Code & Protein Synthesis: practice questions
Chapter 6 — Nucleic Acids and Protein Synthesis · Biology. These are 10 questions from the Magmo3 bank on this lesson, from easy to hard. Solve each one, then open "Show answer and explanation". Magmo3 has 36 questions on this lesson, each with an explanation.
Explanation: Translation (the synthesis of protein from mRNA) takes place on the ribosome in the cytoplasm.
Question 2Easy
The pathway of transfer of genetic information (the central dogma) is?
ARNA → DNA → protein
BDNA → protein directly
CProtein → RNA → DNA
DDNA → RNA → protein
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Correct answer: (D) DNA → RNA → protein
Explanation: The central dogma: information passes from DNA by transcription to RNA, then by translation to protein.
Question 3Easy
The final product of the process of protein synthesis?
AGlucose sugar (a carbohydrate)
BA new DNA molecule (a gene copy)
CA chain of amino acids (a protein)
DAn ATP molecule (an energy carrier)
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Correct answer: (C) A chain of amino acids (a protein)
Explanation: Protein synthesis produces a peptide chain of amino acids in an order determined by the codons.
Question 4Medium
The enzyme responsible for the process of transcription?
ADNA polymerase
BRNA polymerase
CRestriction enzyme
DLigase
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Correct answer: (B) RNA polymerase
Explanation: RNA polymerase builds the mRNA strand from the DNA template.
Question 5Medium
The type of bond that links the amino acids in the resulting protein?
AHydrogen bond
BGlycosidic bond
CIonic bond
DPeptide bond
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Correct answer: (D) Peptide bond
Explanation: Amino acids are joined by peptide bonds to form the protein chain.
Question 6Medium
The start codon in protein synthesis is?
AUAG
BAUG
CUAA
DUGA
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Correct answer: (B) AUG
Explanation: The start codon is AUG and it codes for the amino acid methionine; UAA, UAG, and UGA are stop codons.
Question 7Medium
The number of stop codons is?
AOne
BTwo
CThree (UAA, UAG, and UGA)
DFour
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Correct answer: (C) Three (UAA, UAG, and UGA)
Explanation: There are 3 stop codons that end translation: UAA, UAG, and UGA, and they do not code for amino acids.
Question 8Hard
The codon UUU codes for phenylalanine in bacteria and in humans alike, and phenylalanine is also coded by UUC. Which two properties of the genetic code do these facts show?
AIt is universal and degenerate
BIt is specific to each species and degenerate
CIt is degenerate and ambiguous
DIt is universal and overlapping
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Correct answer: (A) It is universal and degenerate
Explanation: The same codon means the same amino acid in very different organisms, so the code is universal. One amino acid has more than one codon, so it is degenerate. Degenerate does not mean ambiguous: each codon still gives only one amino acid.
Question 9Hard
A protein is made of 150 amino acids. What is the minimum number of nucleotides in the coding region of its gene, counting both DNA strands and the stop codon?
A900
B450
C906
D453
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Correct answer: (C) 906
Explanation: There are 150 codons plus 1 stop codon, so 151 × 3 = 453 nucleotides in the mRNA and in one DNA strand. Counting both strands gives 453 × 2 = 906.
Question 10Hard
An mRNA has the sequence 5'-CCAUGGCUAGAUGGUAAGC-3'. Translation starts at the first AUG from the 5' end and stops at the first stop codon (UAA, UAG or UGA) in the same reading frame. How many amino acids will the polypeptide contain?
A6 amino acids
B5 amino acids
C4 amino acids
D2 amino acids
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Correct answer: (C) 4 amino acids
Explanation: Reading in triplets from the first AUG gives AUG GCU AGA UGG UAA: methionine and three more amino acids, then UAA, which codes for no amino acid, so the polypeptide has 4 amino acids. The UAG and the second AUG inside the sequence are not in this reading frame, so they are ignored.