Chapter 5 — DNA and Genetic Information · Biology. These are 10 questions from the Magmo3 bank on this lesson, from easy to hard. Solve each one, then open "Show answer and explanation". Magmo3 has 35 questions on this lesson, each with an explanation.
How many DNA molecules result from the replication of a single DNA molecule?
AOne molecule
BThree molecules
CFour molecules
DTwo molecules
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Correct answer: (D) Two molecules
Explanation: Replication produces two identical molecules from the single molecule, and each one goes to one of the two resulting cells.
Question 2Easy
What is the shape of the DNA molecule in prokaryotes?
ABranched
BLinear
CSingle helix
DCircular
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Correct answer: (D) Circular
Explanation: Bacterial DNA is a single circular molecule, unlike eukaryotes, whose DNA is linear.
Question 3Easy
During DNA replication, the nitrogenous base adenine (A) pairs with:
AGuanine
BCytosine
CThymine
DUracil
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Correct answer: (C) Thymine
Explanation: According to the complementary base-pairing rule, A pairs with T through two hydrogen bonds.
Question 4Medium
At what point in the cell cycle does DNA replication occur?
ABefore the cell divides
BDuring cell division itself
CIt has no relation to division
DAfter division has ended
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Correct answer: (A) Before the cell divides
Explanation: The cell replicates its DNA before it divides so that each resulting cell receives a complete, identical copy.
Question 5Medium
The small circular DNA molecules found in some bacteria in addition to the main DNA are called:
APlasmids
BHistones
CRibosomes
DNucleosomes
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Correct answer: (A) Plasmids
Explanation: Plasmids are small, extra circular DNA molecules found in some bacteria, separate from the main DNA.
Question 6Medium
What is the importance of complementary base pairing in ensuring the accuracy of replication?
AIt determines the correct base opposite each base on the template
BIt makes the two strands completely identical in their base sequence
CIt prevents polymerase from working at the replication fork
DIt breaks the hydrogen bonds between the two strands of the template
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Correct answer: (A) It determines the correct base opposite each base on the template
Explanation: Because A always pairs with T and G with C, the template exactly determines the order of nucleotides in the new strand, so the copy is accurate.
Question 7Medium
Why is DNA replication described as 'semiconservative'?
ABecause the original molecule stays unchanged and a separate new molecule forms
BBecause each resulting molecule contains one original strand and one new strand
CBecause both resulting molecules are entirely new
DBecause the two original strands stay together in one molecule
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Correct answer: (B) Because each resulting molecule contains one original strand and one new strand
Explanation: In semiconservative replication each old strand acts as a template for a new strand, so each resulting molecule is half old and half new.
Question 8Hard
Compared with the leading strand, building the lagging strand needs:
Afewer primers and less joining by ligase
Bmore primers and more joining by ligase
Ca different polymerase that builds 3' → 5'
Dno helicase, because its template is already single
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Correct answer: (B) more primers and more joining by ligase
Explanation: The lagging strand is built in many fragments, and each fragment starts from its own primer. The fragments must then be joined by ligase. The leading strand grows continuously from a single start.
Question 9Hard
A bacterium lost its plasmid but kept growing and dividing normally, although it could no longer survive a certain antibiotic. What does this suggest?
AThe main chromosome carries the resistance gene, and the plasmid switches it on
BPlasmid DNA is not genetic material, because the cell did not need it
CPlasmids carry the essential genes, which the cell can make again when needed
DEssential genes are on the main chromosome, while plasmids carry useful extra genes
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Correct answer: (D) Essential genes are on the main chromosome, while plasmids carry useful extra genes
Explanation: The cell still lived and divided, so its essential genes are on the main circular chromosome. The plasmid carried an extra advantage, antibiotic resistance, and is still genetic material because it carries genes.
Question 10Hard
A new strand formed during replication has the sequence C-G-A-T-T. What is the sequence of the template strand it was built on?
AA-T-C-G-G
BG-C-U-A-A
CG-C-T-A-A
DC-G-A-T-T
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Correct answer: (C) G-C-T-A-A
Explanation: The new strand is complementary to the template, so the template must be the complement of C-G-A-T-T, which is G-C-T-A-A (C with G and A with T).