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Chapter 5 · DNA Replication: practice questions

Chapter 5 — DNA and Genetic Information · Biology. These are 10 questions from the Magmo3 bank on this lesson, from easy to hard. Solve each one, then open "Show answer and explanation". Magmo3 has 35 questions on this lesson, each with an explanation.

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Question 1Easy

How many DNA molecules result from the replication of a single DNA molecule?

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Correct answer: (D) Two molecules

Explanation: Replication produces two identical molecules from the single molecule, and each one goes to one of the two resulting cells.

Question 2Easy

What is the shape of the DNA molecule in prokaryotes?

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Correct answer: (D) Circular

Explanation: Bacterial DNA is a single circular molecule, unlike eukaryotes, whose DNA is linear.

Question 3Easy

During DNA replication, the nitrogenous base adenine (A) pairs with:

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Correct answer: (C) Thymine

Explanation: According to the complementary base-pairing rule, A pairs with T through two hydrogen bonds.

Question 4Medium

At what point in the cell cycle does DNA replication occur?

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Correct answer: (A) Before the cell divides

Explanation: The cell replicates its DNA before it divides so that each resulting cell receives a complete, identical copy.

Question 5Medium

The small circular DNA molecules found in some bacteria in addition to the main DNA are called:

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Correct answer: (A) Plasmids

Explanation: Plasmids are small, extra circular DNA molecules found in some bacteria, separate from the main DNA.

Question 6Medium

What is the importance of complementary base pairing in ensuring the accuracy of replication?

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Correct answer: (A) It determines the correct base opposite each base on the template

Explanation: Because A always pairs with T and G with C, the template exactly determines the order of nucleotides in the new strand, so the copy is accurate.

Question 7Medium

Why is DNA replication described as 'semiconservative'?

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Correct answer: (B) Because each resulting molecule contains one original strand and one new strand

Explanation: In semiconservative replication each old strand acts as a template for a new strand, so each resulting molecule is half old and half new.

Question 8Hard

Compared with the leading strand, building the lagging strand needs:

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Correct answer: (B) more primers and more joining by ligase

Explanation: The lagging strand is built in many fragments, and each fragment starts from its own primer. The fragments must then be joined by ligase. The leading strand grows continuously from a single start.

Question 9Hard

A bacterium lost its plasmid but kept growing and dividing normally, although it could no longer survive a certain antibiotic. What does this suggest?

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Correct answer: (D) Essential genes are on the main chromosome, while plasmids carry useful extra genes

Explanation: The cell still lived and divided, so its essential genes are on the main circular chromosome. The plasmid carried an extra advantage, antibiotic resistance, and is still genetic material because it carries genes.

Question 10Hard

A new strand formed during replication has the sequence C-G-A-T-T. What is the sequence of the template strand it was built on?

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Correct answer: (C) G-C-T-A-A

Explanation: The new strand is complementary to the template, so the template must be the complement of C-G-A-T-T, which is G-C-T-A-A (C with G and A with T).

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